MUTYH Protein (His tag)

Produktnummer ABIN2726612

Produktdetails

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MUTYH Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MUTYH (full length, N-term HIS tag, transcript variant alpha1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Andere Bezeichnung: Mutyh (MUTYH Produkte)

Synonyme: MUTYH Protein, MGC145569 Protein, CYP2C Protein, MYH Protein, 5730495A01Rik Protein, Mutyha Protein, Mutyhalpha Protein, Mutyhb Protein, Mutyhbeta Protein, Mutyhc Protein, Myh Protein, mutY DNA glycosylase Protein, mutY homolog (E. coli) Protein, A/G-specific adenine DNA glycosylase-like Protein, MUTYH Protein, mutyh Protein, LOC100373318 Protein, Mutyh Protein

Hintergrund: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 59.9 kDa

NCBI Accession: NP_036354

Pathways: DNA Reparatur