Kallikrein 6 Protein (KLK6) (Transcript Variant B) (His tag)

Produktnummer ABIN2724329

Produktdetails

Target: Kallikrein 6 (KLK6)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant B

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Kallikrein 6 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KLK6 / Kallikrein-6 (transcript variant B) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 5 mM HCl, 150 mM NaCl. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Kallikrein 6 (KLK6)

Andere Bezeichnung: Klk6,kallikrein-6 (KLK6 Produkte)

Synonyme: Bssp Protein, Klk7 Protein, PRSS18 Protein, PRSS9 Protein, SP59 Protein, hK6 Protein, Prss9 Protein, AI849898 Protein, BSP Protein, Klk29 Protein, MSP Protein, Prss18 Protein, neurosin Protein, kallikrein related peptidase 6 Protein, kallikrein related-peptidase 6 Protein, kallikrein-6 Protein, KLK6 Protein, Klk6 Protein, LOC100716801 Protein

Hintergrund: This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer&aposs and Parkinson&aposs disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht: 26.2 kDa

NCBI Accession: NP_001012982

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling