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KCNQ4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

KCNQ4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2724049
  • Target Alle KCNQ4 Proteine anzeigen
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 3
    • 2
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses KCNQ4 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human KCNQ4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KCNQ4 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    Andere Bezeichnung
    Kcnq4 (KCNQ4 Produkte)
    Synonyme
    KCNQ4 Protein, k(v)7.4 Protein, kv7.4 Protein, DFNA2 Protein, DFNA2A Protein, KV7.4 Protein, potassium voltage-gated channel subfamily Q member 4 Protein, potassium channel, voltage gated KQT-like subfamily Q, member 4 Protein, potassium voltage-gated channel, subfamily Q, member 4 Protein, KCNQ4 Protein, kcnq4 Protein, Kcnq4 Protein
    Hintergrund
    Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors. [UniProtKB/Swiss-Prot Function]
    Molekulargewicht
    71 kDa
    NCBI Accession
    NP_751895
    Pathways
    Sensory Perception of Sound
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