KCNQ4 Produkte
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
Kategorien
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte KCNQ4 Kategorien
KCNQ4 Antikörper
High quality antibodies with extensive validation data.
KCNQ4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KCNQ4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN3185286
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF, ICC, AA
Validierungen
- (3)
- (4)
Kat. Nr.
ABIN361768
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN563951
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene KCNQ4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308480
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3082236
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3130221
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KCNQ4 Produkten
: "Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss." in: Frontiers in aging neuroscience, Vol. 12, pp. 83, (2020) (PubMed).: "Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea." in: The Journal of physiology, Vol. 598, Issue 1, pp. 151-170, (2020) (PubMed).
: "GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing." in: Frontiers in neural circuits, Vol. 12, pp. 65, (2019) (PubMed).
: "Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection." in: Cardiovascular research, Vol. 110, Issue 1, pp. 40-50, (2016) (PubMed).
: "Role of Kv7 channels in responses of the pulmonary circulation to hypoxia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 308, Issue 1, pp. L48-57, (2015) (PubMed).
: "K(V)7.4 channels participate in the control of rodent renal vascular resting tone." in: Acta physiologica (Oxford, England), Vol. 214, Issue 3, pp. 402-14, (2015) (PubMed).
: "Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats." in: Basic & clinical pharmacology & toxicology, Vol. 110, Issue 2, pp. 145-53, (2014) (PubMed).
: "KCNQ and KCNE potassium channel subunit expression in bovine retinal pigment epithelium." in: Experimental eye research, Vol. 116, pp. 424-32, (2014) (PubMed).
: "The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. E2472-81, (2014) (PubMed).
: "Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 274-84, (2013) (PubMed).
Synonyme und alternative Namen zu KCNQ4
potassium voltage-gated channel subfamily Q member 4 (KCNQ4), potassium channel, voltage gated KQT-like subfamily Q, member 4 (kcnq4), potassium voltage-gated channel subfamily Q member 4 (Kcnq4), potassium voltage-gated channel, subfamily Q, member 4 (Kcnq4), DFNA2, DFNA2A, k(v)7.4, KCNQ4, kv7.4, KV7.4Bezeichner auf Proteinebene für KCNQ4
- potassium voltage-gated channel, KQT-like subfamily, member 4
- potassium voltage-gated channel KQT-like protein 4
- potassium channel KQT-like 4
- potassium channel subunit alpha KvLQT4
- potassium voltage-gated channel subfamily KQT member 4
- KQT-like 4
- potassium voltage-gated channel, subfamily Q, member 4
- voltage-gated potassium channel subunit Kv7.4
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