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KCNT1 Produkte

(Potassium Channel, Subfamily T, Member 1, KCNT1)

Kategorien

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].

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Ausgewählte KCNT1 Kategorien

KCNT1 Antikörper

High quality antibodies with extensive validation data.

KCNT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KCNT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman, Mouse, Rat
ApplikationAA, ICC, IF, IHC, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2482929
Menge100 μg
ReaktivitätHuman, Mouse, Rat
ApplikationAA, ICC, IF, IHC, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2482928
Menge100 μg
ReaktivitätHuman, Mouse, Rat
ApplikationAA, ICC, IF, IHC, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2482925
Menge100 μg

Empfohlene KCNT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätMouse
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3135864
Menge0.25 mg
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3093268
Menge1 mg
ReaktivitätMouse
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3135865
Menge1 mg

Neueste Publikationen zu unseren KCNT1 Produkten

Lu, Bausch, Kallenborn-Gerhardt, Stoetzer, Debruin, Ruth, Geisslinger, Leffler, Lukowski, Schmidtko: "Slack channels expressed in sensory neurons control neuropathic pain in mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 1125-35, 2015 (PubMed).

Cervantes, Vega, Limón, Soto: "Identity, expression and functional role of the sodium-activated potassium current in vestibular ganglion afferent neurons." in: Neuroscience, Vol. 240, pp. 163-75, 2013 (PubMed).

Huang, Wang, Ostertag, Nuwal, Huang, Jan, Basbaum, Jan: "TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing." in: Nature neuroscience, Vol. 16, Issue 9, pp. 1284-90, 2013 (PubMed).

Zhang, Brown, Hyland, Chen, Kronengold, Fleming, Kohn, Moroz, Kaczmarek: "Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 44, pp. 15318-27, 2012 (PubMed).

Wojtovich, Sherman, Nadtochiy, Urciuoli, Brookes, Nehrke: "SLO-2 is cytoprotective and contributes to mitochondrial potassium transport." in: PLoS ONE, Vol. 6, Issue 12, pp. e28287, 2011 (PubMed).

Nuwer, Picchione, Bhattacharjee: "PKA-induced internalization of slack KNa channels produces dorsal root ganglion neuron hyperexcitability." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 42, pp. 14165-72, 2010 (PubMed).

Chen, Kronengold, Yan, Gazula, Brown, Ma, Ferreira, Yang, Bhattacharjee, Sigworth, Salkoff, Kaczmarek: "The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 17, pp. 5654-65, 2009 (PubMed).

Synonyme und alternative Namen zu KCNT1

potassium sodium-activated channel subfamily T member 1 (KCNT1), potassium channel subfamily T member 1 (LOC100436526), potassium sodium-activated channel subfamily T member 1 (Kcnt1), potassium channel, subfamily T, member 1 (Kcnt1), potassium channel, sodium activated subfamily T, member 1 (kcnt1), bA100C15.2, C030030G16Rik, EIEE14, ENFL5, KCa4.1, MGC146594, mKIAA1422, rSlo2, SLACK, Slack, slack, slo2, Slo2.2

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
57582 Homo sapiens
100436526 Pongo abelii
100588032 Nomascus leucogenys
60444 Rattus norvegicus
227632 Mus musculus
395248 Gallus gallus
464846 Pan troglodytes
491258 Canis lupus familiaris
529468 Bos taurus
779818 Xenopus (Silurana) tropicalis
100016518 Monodelphis domestica
100734549 Cavia porcellus

Bezeichner auf Proteinebene für KCNT1

  • potassium channel subfamily T member 1
  • potassium channel, subfamily T, member 1
  • potassium channel subfamily T member 1-like
  • potassium channel subunit (Slack)
  • sequence like a calcium-activated potassium channel subunit
  • sodium-activated potassium channel
  • potassium channel subunit
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