Interleukin enhancer-binding factor 3 (ILF3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2723411

Produktdetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Myc-DYKDDDDK Tag

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ILF3 / DRBF (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: Ilf3,drbf (ILF3 Produkte)

Synonyme: CBTF Protein, DRBF Protein, DRBP76 Protein, MMP4 Protein, MPHOSPH4 Protein, MPP4 Protein, NF-AT-90 Protein, NF110 Protein, NF110b Protein, NF90 Protein, NF90a Protein, NF90b Protein, NFAR Protein, NFAR-1 Protein, NFAR2 Protein, TCP110 Protein, TCP80 Protein, MBII-26 Protein, ilf3 Protein, wu:fb37d07 Protein, wu:fb94b02 Protein, zgc:77030 Protein, 4F.1 Protein, cbtf122 Protein, ilf3-A Protein, ubp3 Protein, ubp4 Protein, xilf3 Protein, interleukin enhancer binding factor 3 Protein, interleukin enhancer binding factor 3b Protein, interleukin enhancer binding factor 3 S homeolog Protein, ILF3 Protein, Ilf3 Protein, ilf3b Protein, ilf3.S Protein

Hintergrund: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014].

Molekulargewicht: 95.2 kDa

NCBI Accession: NP_036350

Pathways: M Phase