GLI1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721923

Produktdetails

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GLI1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human GLI1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: Gli1 (GLI1 Produkte)

Synonyme: GLI Protein, Gli Protein, Gli-1 Protein, gli1.1 Protein, AV235269 Protein, Zfp-5 Protein, Zfp5 Protein, GLI family zinc finger 1 Protein, GLI family zinc finger 1 S homeolog Protein, GLI-Kruppel family member GLI1 Protein, GLI1 Protein, Gli1 Protein, gli1.S Protein, gli1 Protein

Hintergrund: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 117.7 kDa

NCBI Accession: NP_005260

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis