FKBP5 Protein (His tag)

Produktnummer ABIN2721217

Produktdetails

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FKBP5 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human FKBP5 / FKBP51 (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Andere Bezeichnung: Fkbp5,fkbp51 (FKBP5 Produkte)

Synonyme: FKBP5 Protein, FKBP-5 Protein, AIG6 Protein, FKBP51 Protein, FKBP54 Protein, P54 Protein, PPIase Protein, Ptg-10 Protein, D17Ertd592e Protein, Dit1 Protein, si:zc263a23.8 Protein, wu:fc31g11 Protein, wu:fl87b03 Protein, zgc:64082 Protein, FK506 binding protein 5 Protein, FKBP5 Protein, fkbp5 Protein, Fkbp5 Protein

Hintergrund: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].

Molekulargewicht: 51 kDa

NCBI Accession: NP_001139247