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FKBP5 Produkte

(FK506 Binding Protein 5 (FKBP5))

Kategorien

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].

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Ausgewählte FKBP5 Kategorien

FKBP5 Antikörper

High quality antibodies with extensive validation data.

FKBP5 ELISA Kits

Reliable ELISA kits for a wide range of species.

FKBP5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FKBP5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p)
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN515669
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN7260887
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (7)
Kat. Nr. ABIN1679852
Menge 100 μg
Datenblatt Datenblatt

Empfohlene FKBP5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955923
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955924
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882891
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FKBP5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1354130
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122977
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3123299
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FKBP5 Produkten

Mata-Greenwood, Jackson, Pearce, Zhang: "Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity." in: Journal of molecular endocrinology, (2015) (PubMed).

Romano, Xiao, Nakaya, DAngelillo, Chang, Jin, Hausch, Masullo, Feng, Romano, Sun: "FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma." in: Nucleic acids research, Vol. 43, Issue 14, pp. 6983-93, (2015) (PubMed).

Romano, DAngelillo, Staibano, Simeone, DArrigo, Ascierto, Scalvenzi, Mascolo, Ilardi, Merolla, Jovarauskaite, Romano: "Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients." in: Pigment cell & melanoma research, Vol. 28, Issue 4, pp. 442-52, (2015) (PubMed).

Yang, Zhang, Pei, Xu, Li, Yu: "FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells." in: Archives of medical science : AMS, Vol. 11, Issue 5, pp. 1074-80, (2015) (PubMed).

Romano, DAngelillo, DArrigo, Staibano, Greco, Brunetti, Scalvenzi, Bisogni, Scala, Romano: "FKBP51 increases the tumour-promoter potential of TGF-beta." in: Clinical and translational medicine, Vol. 3, Issue 1, pp. 1, (2014) (PubMed).

Romano, Staibano, Greco, Brunetti, Nappo, Ilardi, Martinelli, Sorrentino, Di Pace, Mascolo, Bisogni, Scalvenzi, Alfano, Romano: "FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential." in: Cell death & disease, Vol. 4, pp. e578, (2013) (PubMed).

van Lierop, Alkema, Laskewitz, Dijkema, van der Maaden, Smit, Plate, Conti, Jans, Timmers, van Boeckel, Lusher, McGuire, van Schaik, de Vlieg, Smeets, Hofstra, Boots, van Duin, Ingelse, Schoonen et al.: "Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. ..." in: PLoS ONE, Vol. 7, Issue 11, pp. e48385, (2012) (PubMed).

Horibe, Kohno, Haramoto, Ohara, Kawakami: "Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent." in: Journal of translational medicine, Vol. 9, pp. 8, (2011) (PubMed).

Synonyme und alternative Namen zu FKBP5

FK506 binding protein 5 (FKBP5), FK506 binding protein 5 (fkbp5), FK506 binding protein 5 (Fkbp5), AIG6, D17Ertd592e, Dit1, FKBP-5, FKBP5, FKBP51, FKBP54, P54, PPIase, Ptg-10, si:zc263a23.8, wu:fc31g11, wu:fl87b03, zgc:64082

Bezeichner auf Proteinebene für FKBP5

  • FK506 binding protein 5
  • FK506-binding protein 5
  • PPIase FKBP5
  • peptidyl-prolyl cis-trans isomerase FKBP5
  • rotamase
  • 51 kDa FK506-binding protein 5
  • 51 kDa FKBP
  • 54 kDa progesterone receptor-associated immunophilin
  • FF1 antigen
  • FKBP-5
  • FKBP-51
  • HSP90-binding immunophilin
  • T-cell FK506-binding protein
  • androgen-regulated protein 6
  • peptidylprolyl cis-trans isomerase
  • 51 kDa FK506-binding protein
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