EIF4G1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720103

Produktdetails

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EIF4G1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human EIF4G1 / EIF4F (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Andere Bezeichnung: Eif4g1,eif4f (EIF4G1 Produkte)

Synonyme: EIF4GI Protein, CG10811 Protein, Dmel\\CG10811 Protein, EIF4G Protein, Eif4G Protein, deIF4G Protein, eIF-4G Protein, eIF4g Protein, p200 Protein, EIF4G1 Protein, wu:fb50a05 Protein, wu:fc60b06 Protein, eif4g Protein, CUCUMOVIRUS MULTIPLICATION 2 Protein, CUM2 Protein, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G Protein, eukaryotic translation initiation factor 4G Protein, DDBDRAFT_0217646 Protein, DDBDRAFT_0217647 Protein, DDBDRAFT_0234257 Protein, DDB_0217646 Protein, DDB_0217647 Protein, DDB_0234257 Protein, NV18824 Protein, EIF-4G1 Protein, EIF4F Protein, P220 Protein, PARK18 Protein, p220 Protein, E030015G23Rik Protein, eIF4GI Protein, eukaryotic translation initiation factor 4 gamma 1 Protein, eukaryotic translation initiation factor 4G Protein, eukaryotic translation initiation factor 4 gamma, 1a Protein, eukaryotic translation initiation factor 4 gamma, 1 S homeolog Protein, eukaryotic initiation factor Protein, eukaryotic translation initiation factor 4 gamma Protein, eukaryotic translation initiation factor 4 gamma, 1 Protein, eukaryotic translation initiation factor 4, gamma 1 Protein, EIF4G1 Protein, eIF4G Protein, eif4g1a Protein, LOC704923 Protein, eif4g1.S Protein, EIF4G Protein, eIF4g Protein, Eif4g Protein, Eif4g1 Protein

Hintergrund: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Molekulargewicht: 175.3 kDa

NCBI Accession: NP_937884