EIF4G1 Produkte
(Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
Kategorien
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010].
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Ausgewählte EIF4G1 Kategorien
EIF4G1 Antikörper
High quality antibodies with extensive validation data.
EIF4G1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EIF4G1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (7)
Kat. Nr.
ABIN515213
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7263569
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN515212
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene EIF4G1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228193
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene EIF4G1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1352615
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122847
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352616
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EIF4G1 Produkten
: "Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia." in: American journal of physiology. Endocrinology and metabolism, Vol. 311, Issue 4, pp. E791-E801, (2016) (PubMed).: "DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3764-75, (2015) (PubMed).
: "Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA." in: Molecular and cellular biology, Vol. 34, Issue 3, pp. 439-51, (2014) (PubMed).
: "Dynamic regulation of the translation initiation helicase complex by mitogenic signal transduction to eukaryotic translation initiation factor 4G." in: Molecular and cellular biology, Vol. 33, Issue 5, pp. 937-46, (2013) (PubMed).
: "Anabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E674-86, (2012) (PubMed).
: "A cellular response linking eIF4AI activity to eIF4AII transcription." in: RNA (New York, N.Y.), Vol. 18, Issue 7, pp. 1373-84, (2012) (PubMed).
: "Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 3, pp. 1046-51, (2011) (PubMed).
: "Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2947-59, (2011) (PubMed).
: "Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs." in: The Journal of nutrition, Vol. 141, Issue 12, pp. 2152-8, (2011) (PubMed).
: "Dysregulation of mTOR signaling in fragile X syndrome." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 2, pp. 694-702, (2010) (PubMed).
Synonyme und alternative Namen zu EIF4G1
eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), eukaryotic translation initiation factor 4G (eIF4G), eukaryotic translation initiation factor 4 gamma, 1a (eif4g1a), eukaryotic translation initiation factor 4 gamma 1 (LOC704923), eukaryotic translation initiation factor 4 gamma, 1 S homeolog (eif4g1.S), eukaryotic translation initiation factor 4G (EIF4G), eukaryotic initiation factor (EIF4G), eukaryotic translation initiation factor 4 gamma (eIF4g), eukaryotic translation initiation factor 4 gamma (Eif4g), eukaryotic translation initiation factor 4 gamma, 1 (Eif4g1), eukaryotic translation initiation factor 4, gamma 1 (Eif4g1), CG10811, CUCUMOVIRUS MULTIPLICATION 2, CUM2, DDBDRAFT_0217646, DDBDRAFT_0217647, DDBDRAFT_0234257, DDB_0217646, DDB_0217647, DDB_0234257, deIF4G, Dmel\\CG10811, E030015G23Rik, eIF-4G, EIF-4G1, EIF4F, EIF4G, Eif4G, eIF4g, eif4g, EIF4G1, EIF4GI, eIF4GI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, eukaryotic translation initiation factor 4G, NV18824, p200, P220, p220, PARK18, wu:fb50a05, wu:fc60b06Bezeichner auf Proteinebene für EIF4G1
- eukaryotic translation initiation factor 4 gamma 1
- CG10811-PA
- CG10811-PB
- CG10811-PC
- Eukaryotic-initiation-factor-4G
- eIF-4G
- eIF4G-PA
- eIF4G-PB
- eIF4G-PC
- eukaryotic initiation factor 4G
- translation initiation factor
- translation initiation factor eIF4G
- eukaryotic translation initiation factor 4 gamma, 1
- fb50a05
- eukaryotic initiation factor
- eukaryotic translation initiation factor 4 gamma
- eukaryotic translation initiation factor 4 gamma 1-like
- EIF4-gamma
- eIF-4-gamma 1
- eucaryotic translation initiation factor 4G
- eIF-4G 1
- eIF-4G1
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