DCTN3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719849

Produktdetails

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DCTN3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Dynactin subunit 3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Andere Bezeichnung: Dynactin Subunit 3 (Dctn3 Produkte)

Synonyme: zgc:92471 Protein, wu:fc38g10 Protein, p24 Protein, NV12799 Protein, DCTN-22 Protein, DCTN22 Protein, dynactin 3 (p22) Protein, dynactin subunit 3 Protein, dynactin 3 Protein, dctn3 Protein, LOC658790 Protein, Dctn3 Protein, DCTN3 Protein

Hintergrund: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 20.9 kDa

NCBI Accession: NP_009165

Pathways: M Phase