ARPC4 Protein (His tag)

Produktnummer ABIN2714941

Produktdetails

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ARPC4 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARPC4 / ARC20 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Andere Bezeichnung: Arpc4,arc20 (ARPC4 Produkte)

Synonyme: ARC20 Protein, P20-ARC Protein, 20kDa Protein, 5330419I20Rik Protein, AI327076 Protein, p20-Arc Protein, arc20 Protein, p20-arc Protein, ARPC4 Protein, fa07b12 Protein, wu:fa07b12 Protein, zgc:77932 Protein, actin related protein 2/3 complex subunit 4 Protein, Actin-related protein 2/3 complex subunit 4 Protein, actin-related protein 2/3 complex subunit 4 Protein, actin related protein 2/3 complex, subunit 4 Protein, actin related protein 2/3 complex subunit 4 S homeolog Protein, actin related protein 2/3 complex, subunit 4, 20kDa Protein, ARPC4 Protein, PTRG_00644 Protein, CMU_000110 Protein, Arpc4 Protein, arpc4 Protein, arpc4.S Protein

Hintergrund: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.

Molekulargewicht: 19.5 kDa

NCBI Accession: NP_005709

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization