alpha Actinin 4 Protein (Myc-DYKDDDDK Tag)
-
- Target Alle alpha Actinin 4 (ACTN4) Proteine anzeigen
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Protein-Typ
- Recombinant
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses alpha Actinin 4 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
-
- Recombinant human Alpha-actinin-4 / ACTN4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACTN4 Protein
-
-
- Applikationshinweise
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
-
The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
Alpha-Actinin-4 is a Possible Target Protein for Aristolochic Acid I in Human Kidney Cells In Vitro." in: The American journal of Chinese medicine, Vol. 44, Issue 2, pp. 291-304, (2016) (PubMed).
: "
-
Alpha-Actinin-4 is a Possible Target Protein for Aristolochic Acid I in Human Kidney Cells In Vitro." in: The American journal of Chinese medicine, Vol. 44, Issue 2, pp. 291-304, (2016) (PubMed).
-
- Target
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Andere Bezeichnung
- alpha-Actinin-4,actn4 (ACTN4 Produkte)
- Synonyme
- fsgs Protein, fsgs1 Protein, C77391 Protein, ACTININ-4 Protein, FSGS Protein, FSGS1 Protein, wu:fb53f05 Protein, zgc:63508 Protein, actinin alpha 4 Protein, actinin, alpha 4 Protein, actinin alpha 4 S homeolog Protein, actn4 Protein, ACTN4 Protein, Actn4 Protein, actn4.S Protein
- Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
- Molekulargewicht
- 104.7 kDa
- NCBI Accession
- NP_004915
- Pathways
- Proton Transport
-