BCAM Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713528

Produktdetails

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BCAM Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CD239 / BCAM (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Andere Bezeichnung: Cd239,bcam (BCAM Produkte)

Synonyme: cd239 Protein, msk19 Protein, MGC81012 Protein, LU Protein, prr2 Protein, zgc:154034 Protein, 1200005K12Rik Protein, B-CAM Protein, Gplu Protein, Lu Protein, AU Protein, CD239 Protein, MSK19 Protein, basal cell adhesion molecule (Lutheran blood group) Protein, basal cell adhesion molecule (Lutheran blood group) L homeolog Protein, basal cell adhesion molecule Protein, bcam Protein, bcam.L Protein, BCAM Protein, Bcam Protein

Hintergrund: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 64.2 kDa

NCBI Accession: NP_005572