BCAM Produkte
(Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))
Kategorien
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Ausgewählte BCAM Kategorien
BCAM Antikörper
High quality antibodies with extensive validation data.
BCAM ELISA Kits
Reliable ELISA kits for a wide range of species.
BCAM Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BCAM Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IP
Validierungen
- (6)
Kat. Nr.
ABIN7442009
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
- (6)
Kat. Nr.
ABIN7193338
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7145263
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene BCAM ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954046
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5510708
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN625265
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BCAM Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273932
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273935
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273931
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BCAM Produkten
: "An Anti-Human Lutheran Glycoprotein Phage Antibody Inhibits Cell Migration on Laminin-511: Epitope Mapping of the Antibody." in: PLoS ONE, Vol. 12, Issue 1, pp. e0167860, (2017) (PubMed).: "BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 19, pp. 4923-4933, (2016) (PubMed).
: "Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11512-21, (2014) (PubMed).
: "The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 30990-1001, (2013) (PubMed).
: "An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5." in: PLoS ONE, Vol. 6, Issue 8, pp. e23329, (2011) (PubMed).
: "Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of ..." in: Journal of bacteriology, Vol. 189, Issue 11, pp. 3977-86, (2007) (PubMed).
: "A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane." in: Blood, Vol. 101, Issue 10, pp. 4180-8, (2003) (PubMed).
Synonyme und alternative Namen zu BCAM
basal cell adhesion molecule (Lutheran blood group) (bcam), basal cell adhesion molecule (Lutheran blood group) L homeolog (bcam.L), basal cell adhesion molecule (Lutheran blood group) (BCAM), basal cell adhesion molecule (BCAM), basal cell adhesion molecule (Bcam), basal cell adhesion molecule (Lutheran blood group) (Bcam), 1200005K12Rik, AU, B-CAM, cd239, CD239, Gplu, LU, Lu, MGC81012, msk19, MSK19, prr2, zgc:154034Bezeichner auf Proteinebene für BCAM
- basal cell adhesion molecule (Lutheran blood group)
- Auberger b antigen
- Lutheran blood group
- basal cell adhesion molecule (Lu and Au blood groups)
- basal cell adhesion molecule
- LU
- basal cell adhesion molecule-like
- B-CAM cell surface glycoprotein
- lutheran antigen
- lutheran glycoprotein
- B-cell adhesion molecule
- F8/G253 antigen
- antigen identified by monoclonal antibody F8
- glycoprotein 95kDa
- Lutheran blood group (Auberger b antigen included)
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