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BCL10 Produkte

(B-Cell CLL/lymphoma 10 (BCL10))
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008].

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Ausgewählte BCL10 Kategorien

BCL10 Antikörper

High quality antibodies with extensive validation data.

BCL10 ELISA Kits

Reliable ELISA kits for a wide range of species.

BCL10 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BCL10 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (3)
  • (4)
Kat. Nr. ABIN1944800
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC, ELISA, FACS, ICC
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN1724629
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, FACS, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN654655
Menge 400 μL
Datenblatt Datenblatt

Empfohlene BCL10 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965103
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962056
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4881949
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BCL10 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346536
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3120204
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3089983
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BCL10 Produkten

Borthakur, Bhattacharyya, Alrefai, Tobacman, Ramaswamy, Dudeja: "Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent." in: Inflammatory bowel diseases, Vol. 16, Issue 4, pp. 593-603, (2010) (PubMed).

Bhattacharyya, Gill, Chen, Zhang, Linhardt, Dudeja, Tobacman: "Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10550-8, (2008) (PubMed).

Bhattacharyya, Pant, Dudeja, Tobacman: "Development, evaluation, and application of a highly sensitive microtiter plate ELISA for human Bcl10 protein." in: Journal of immunoassay & immunochemistry, Vol. 28, Issue 3, pp. 173-88, (2007) (PubMed).

Nagy, Rui, Stepkowski, Karras, Kirken: "A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5032-40, (2006) (PubMed).

Ye, Gong, Liu, Hamoudi, Shirali, Ho, Chott, Streubel, Siebert, Gesk, Martin-Subero, Radford, Banerjee, Nicholson, Ranaldi, Remstein, Gao, Zheng, Isaacson, Dogan, Du: "MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression." in: The Journal of pathology, Vol. 205, Issue 3, pp. 293-301, (2005) (PubMed).

Xue, Morris, Orihuela, Tuomanen, Cui, Wen, Wang: "Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells." in: Nature immunology, Vol. 4, Issue 9, pp. 857-65, (2003) (PubMed).

Wang, Guo, Huang, Ke, Poyet, Manji, Merriam, Glucksmann, DiStefano, Alnemri, Bertin: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, (2001) (PubMed).

Lucas, Yonezumi, Inohara, McAllister-Lucas, Abazeed, Chen, Yamaoka, Seto, Nunez: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).

Ye, Dogan, Karran, Willis, Chen, Wlodarska, Dyer, Isaacson, Du: "BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma." in: The American journal of pathology, Vol. 157, Issue 4, pp. 1147-54, (2000) (PubMed).

Du, Peng, Liu, Hamoudi, Diss, Willis, Ye, Dogan, Wotherspoon, Dyer, Isaacson: "BCL10 gene mutation in lymphoma." in: Blood, Vol. 95, Issue 12, pp. 3885-90, (2000) (PubMed).

Synonyme und alternative Namen zu BCL10

B-cell CLL/lymphoma 10 (BCL10), B-cell CLL/lymphoma 10 (Bcl10), B-cell CLL/lymphoma 10 (bcl10), B-cell lymphoma/leukemia 10-like (LOC100223183), B cell leukemia/lymphoma 10 (Bcl10), B-cell lymphoma/leukemia 10 (bcl10), AI132454, BCL-10, BCL10, bcl10, c-E10, C81403, CARMEN, cE10, CIPER, CLAP, mE10, ME10

Bezeichner auf Proteinebene für BCL10

  • B-cell lymphoma/leukemia 10
  • CARD containing molecule enhancing NF-kB
  • CARD-containing apoptotic signaling protein
  • CARD-containing molecule enhancing NF-kappa-B
  • CARD-containing proapoptotic protein
  • CED-3/ICH-1 prodomain homologous E10-like regulator
  • cCARMEN
  • caspase-recruiting domain-containing protein
  • cellular homolog of vCARMEN
  • cellular-E10
  • hCLAP
  • mammalian CARD-containing adapter molecule E10
  • B-cell leukemia/lymphoma 10
  • R-RCD1
  • RCD
  • bcl-10
  • B-cell lymophoma 10 protein
  • B-cell CLL/lymphoma 10
  • B cell lymphoma/leukemia 10
  • CARD-like apoptotic protein
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