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BCL6 Produkte

(B-Cell CLL/lymphoma 6 (BCL6))
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

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Ausgewählte BCL6 Kategorien

BCL6 Antikörper

High quality antibodies with extensive validation data.

BCL6 ELISA Kits

Reliable ELISA kits for a wide range of species.

BCL6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BCL6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN3187827
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN749843
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, IHC, ICC, Neut
Validierungen
  • (5)
Kat. Nr. ABIN5611253
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene BCL6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965111
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380950
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951387
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BCL6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121962
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346576
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3133993
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BCL6 Produkten

Huang, Zhang, Hou, Wang, Liu, Zhang, Chen, Zhu: "LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 194, (2018) (PubMed).

Szabó, Gáspár, Dajnoki, Papp, Fábos, Szegedi, Zeher: "Expansion of circulating follicular T helper cells associates with disease severity in childhood atopic dermatitis." in: Immunology letters, Vol. 189, pp. 101-108, (2017) (PubMed).

Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).

Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).

Crotty: "Follicular helper CD4 T cells (TFH)." in: Annual review of immunology, Vol. 29, pp. 621-63, (2011) (PubMed).

Crotty, Johnston, Schoenberger: "Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation." in: Nature immunology, Vol. 11, Issue 2, pp. 114-20, (2010) (PubMed).

Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).

Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).

Johnston, Poholek, DiToro, Yusuf, Eto, Barnett, Dent, Craft, Crotty: "Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1006-10, (2009) (PubMed).

Synonyme und alternative Namen zu BCL6

B-cell CLL/lymphoma 6 L homeolog (bcl6.L), B-cell CLL/lymphoma 6 (bcl6), B-cell CLL/lymphoma 6 (BCL6), B cell leukemia/lymphoma 6 (Bcl6), B-cell CLL/lymphoma 6 (Bcl6), bcl5, Bcl5, BCL5, bcl6a, BCL6A, laz3, LAZ3, MGC132260, zbtb27, ZBTB27, znf51, ZNF51

Bezeichner auf Proteinebene für BCL6

  • B-cell CLL/lymphoma 6
  • B-cell CLL/lymphoma 6 (zinc finger protein 51)
  • B-cell lymphoma 6 protein
  • zinc finger protein 51
  • B-cell leukemia/lymphoma 5
  • B-cell leukemia/lymphoma 6
  • B-cell lymphoma 6 protein homolog
  • B-cell lymphoma 5 protein
  • B-cell lymphoma 6 protein transcript
  • BCL-5
  • BCL-6
  • cys-his2 zinc finger transcription factor
  • lymphoma-associated zinc finger gene on chromosome 3
  • protein LAZ-3
  • zinc finger and BTB domain-containing protein 27
  • zinc finger transcription factor BCL6S
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