Caspase 10 Protein (His tag)
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- Target Alle Caspase 10 (CASP10) Proteine anzeigen
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- Protein-Typ
- Recombinant
- Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Caspase 10 Protein ist gelabelt mit His tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Caspase-10 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CASP10 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the N-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- Andere Bezeichnung
- Caspase-10 (CASP10 Produkte)
- Synonyme
- xCaspase-10 Protein, alps2 Protein, caspace-10 Protein, caspase-10 Protein, flice2 Protein, mch4 Protein, xCaspace-10 Protein, ALPS2 Protein, FLICE2 Protein, MCH4 Protein, caspase 10 S homeolog Protein, caspase 10 Protein, caspase-10 Protein, casp10.S Protein, casp10 Protein, CASP10 Protein, Casp10 Protein, LOC100848685 Protein
- Hintergrund
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molekulargewicht
- 58.8 kDa
- NCBI Accession
- NP_116759
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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