CPN1 Protein (His tag)

Produktnummer ABIN2713157

Produktdetails

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CPN1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Carboxypeptidase N catalytic chain (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Andere Bezeichnung: Carboxypeptidase N Catalytic Chain (CPN1 Produkte)

Synonyme: CPN Protein, SCPN Protein, Cpn Protein, cb1037 Protein, fa99g08 Protein, wu:fa99g08 Protein, zgc:77485 Protein, cpn Protein, scpn Protein, 0610011F20Rik Protein, carboxypeptidase N subunit 1 Protein, carboxypeptidase N, polypeptide 1 Protein, carboxypeptidase N subunit 1 S homeolog Protein, CPN1 Protein, Cpn1 Protein, cpn1 Protein, cpn1.S Protein

Hintergrund: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

Molekulargewicht: 50 kDa

NCBI Accession: NP_001299

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process