CYP1A1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712753

Produktdetails

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CYP1A1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CYP1A1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Andere Bezeichnung: Cyp1a1 (CYP1A1 Produkte)

Synonyme: AHH Protein, AHRR Protein, CP11 Protein, CYP1 Protein, P1-450 Protein, P450-C Protein, P450DX Protein, Cyp1a2 Protein, P450-1 Protein, cyp1a1 Protein, CYP1A1 Protein, CYPIA1 Protein, Cyp45c Protein, Cypc45c Protein, P-450MC Protein, wu:fb63b04 Protein, zfCYP1A Protein, zgc:109747 Protein, ahh Protein, ahrr Protein, cp11 Protein, cyp1 Protein, cyp1a Protein, p1-450 Protein, p450-c Protein, p450dx Protein, cytochrome P450 family 1 subfamily A member 1 Protein, cytochrome P450 1A1 Protein, cytochrome P450, family 1, subfamily a, polypeptide 1 Protein, cytochrome P450, family 1, subfamily A, polypeptide 1 Protein, cytochrome P450 family 1 subfamily D polypeptide 1 Protein, cytochrome P4501A1 Protein, polycyclic hydrocarbon-inducible cytochrome P450c Protein, cytochrome P450, family 1, subfamily A Protein, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 Protein, cytochrome P450 family 1 subfamily A member 1 L homeolog Protein, CYP1A1 Protein, CpipJ_CPIJ010542 Protein, Cyp1a1 Protein, cyp1d1 Protein, LOC100328613 Protein, cyp1a Protein, LOC102129994 Protein, cyp1a1.L Protein

Hintergrund: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 58 kDa

NCBI Accession: NP_000490

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha