CYP17A1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712752

Produktdetails

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CYP17A1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CYP17A1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Andere Bezeichnung: Cyp17a1 (CYP17A1 Produkte)

Synonyme: cyp17 Protein, CYPXVII Protein, P450c17 Protein, cyp17a1 Protein, P450-C17 Protein, wu:fi13g04 Protein, wu:fi17b11 Protein, wu:fi31c08 Protein, zgc:136516 Protein, zgc:66494 Protein, P45017A1 Protein, CYP17 Protein, CPT7 Protein, P450C17 Protein, S17AH Protein, Cyp17 Protein, p450c17 Protein, cytochrome P450 17A1 Protein, cytochrome P450, family 17, subfamily A, polypeptide 1 Protein, steroidogenic cytochrome P450 17-hydroxylase/lyase Protein, cytochrome P450 family 17 subfamily A member 1 L homeolog Protein, cytochrome P450 family 17 subfamily A member 1 Protein, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase Protein, cytochrome P450, family 17, subfamily a, polypeptide 1 Protein, cytochrome P450c17 Protein, CpipJ_CPIJ010537 Protein, CpipJ_CPIJ010543 Protein, PTRG_02047 Protein, cyp17a1 Protein, cyp17 Protein, cyp17a1.L Protein, CYP17A1 Protein, Cyp17a1 Protein

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Molekulargewicht: 57.2 kDa

NCBI Accession: NP_000093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin