CYP17A1 Protein (AA 1-507) (His tag)

Produktnummer ABIN1473924

Produktdetails

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-507

Spezies: Ratte

Quelle: Hefe

Aufreinigungstag / Konjugat: Dieses CYP17A1 Protein ist gelabelt mit His tag.

Applikation: ELISA

Sequenz: MWELVGLLLL ILAYFFWVKS KTPGAKLPRS LPSLPLVGSL PFLPRRGHMH VNFFKLQEKY GPIYSLRLGT TTTVIIGHYQ LAREVLIKKG KEFSGRPQMV TQSLLSDQGK GVAFADAGSS WHLHRKLVFS TFSLFKDGQK LEKLICQEAK SLCDMMLAHD KESIDLSTPI FMSVTNIICA ICFNISYEKN DPKLTAIKTF TEGIVDATGD RNLVDIFPWL TIFPNKGLEV IKGYAKVRNE VLTGIFEKCR EKFDSQSISS LTDILIQAKM NSDNNNSCEG RDPDVFSDRH ILATVGDIFG AGIETTTTVL KWILAFLVHN PEVKKKIQKE IDQYVGFSRT PTFNDRSHLL MLEATIREVL RIRPVAPMLI PHKANVDSSI GEFTVPKDTH VVVNLWALHH DENEWDQPDQ FMPERFLDPT GSHLITPTQS YLPFGAGPRS CIGEALARQE LFVFTALLLQ RFDLDVSDDK QLPRLEGDPK VVFLIDPFKV KITVRQAWMD AQAEVST

Spezifität: Rattus norvegicus (Rat)

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: > 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Antigendetails

Target: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Andere Bezeichnung: Steroid 17-alpha-hydroxylase/17,20 lyase (Cyp17a1) (CYP17A1 Produkte)

Synonyme: cyp17 Protein, CYPXVII Protein, P450c17 Protein, cyp17a1 Protein, P450-C17 Protein, wu:fi13g04 Protein, wu:fi17b11 Protein, wu:fi31c08 Protein, zgc:136516 Protein, zgc:66494 Protein, P45017A1 Protein, CYP17 Protein, CPT7 Protein, P450C17 Protein, S17AH Protein, Cyp17 Protein, p450c17 Protein, cytochrome P450 17A1 Protein, cytochrome P450, family 17, subfamily A, polypeptide 1 Protein, steroidogenic cytochrome P450 17-hydroxylase/lyase Protein, cytochrome P450 family 17 subfamily A member 1 L homeolog Protein, cytochrome P450 family 17 subfamily A member 1 Protein, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase Protein, cytochrome P450, family 17, subfamily a, polypeptide 1 Protein, cytochrome P450c17 Protein, CpipJ_CPIJ010537 Protein, CpipJ_CPIJ010543 Protein, PTRG_02047 Protein, cyp17a1 Protein, cyp17 Protein, cyp17a1.L Protein, CYP17A1 Protein, Cyp17a1 Protein

Hintergrund: Recommended name: Steroid 17-alpha-hydroxylase/17,20 lyase.
EC= 1.14.99.9.
Alternative name(s): CYPXVII Cytochrome P450 17A1 Cytochrome P450-C17.
Short name= Cytochrome P450c17

UniProt: P11715

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin