Cortactin Protein (CTTN) (DYKDDDDK Tag)

Produktnummer ABIN2712519

Produktdetails

Target: Cortactin (CTTN)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Insect cells (Sf9)

Aufreinigungstag / Konjugat: Dieses Cortactin Protein ist gelabelt mit DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Cortactin (full length, C-term DDK tag, transcript variant 2) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Cortactin (CTTN)

Andere Bezeichnung: Cortactin (CTTN Produkte)

Synonyme: EMS1 Protein, 1110020L01Rik Protein, Ems1 Protein, Cttnb Protein, CG3637 Protein, Dmel\CG3637 Protein, cortactin Protein, cttn Protein, CTTN1 Protein, P85.25 Protein, Cttn Protein, ems1 Protein, CTTN Protein, cortactin Protein, CG3637 gene product from transcript CG3637-RD Protein, cortactin S homeolog Protein, cortactin L homeolog Protein, src substrate cortactin Protein, Src substrate cortactin Protein, CTTN Protein, Cttn Protein, Cortactin Protein, cttn.S Protein, cttn.L Protein, cttn Protein, CpipJ_CPIJ006351 Protein, Bm1_57220 Protein, LOC100533277 Protein

Hintergrund: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Molekulargewicht: 57.3 kDa

NCBI Accession: NP_612632

Pathways: MAPK Signalweg