COPS5 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712494

Produktdetails

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses COPS5 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human COPS5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Andere Bezeichnung: Cops5 (COPS5 Produkte)

Synonyme: BcDNA.LD14392 Protein, BcDNA:LD14392 Protein, CG14884 Protein, CH5 Protein, CSN-5 Protein, Csn5 Protein, DCH5 Protein, Dch5 Protein, Dmel\\CG14884 Protein, JAB1 Protein, JAB1/CSN5 Protein, Jab1 Protein, JadBp Protein, csn5 Protein, dch5 Protein, jab1/csn5 Protein, l(3)89Cf Protein, l(3)L4032 Protein, l(3)M203 Protein, quo Protein, COPS5 Protein, MGC76063 Protein, AI303502 Protein, CSN5 Protein, Mov34 Protein, Sgn5 Protein, zgc:73130 Protein, MOV-34 Protein, SGN5 Protein, COP9 signalosome subunit 5 Protein, COP9 signalosome complex subunit 5 Protein, COP9 signalosome subunit 5 S homeolog Protein, CSN5 Protein, COPS5 Protein, cops5 Protein, CpipJ_CPIJ012314 Protein, Bm1_46585 Protein, VDBG_06932 Protein, LOAG_01443 Protein, csn5 Protein, Cops5 Protein, cops5.S Protein, csn-5 Protein

Hintergrund: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Molekulargewicht: 37.4 kDa

NCBI Accession: NP_006828

Pathways: Zellzyklus