EBP Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2712409

Produktdetails

Target: EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses EBP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human D8-D7 sterol isomerase protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))

Andere Bezeichnung: d8-d7 Sterol Isomerase (EBP Produkte)

Synonyme: cdpx2 Protein, cho2 Protein, cpx Protein, cpxd Protein, zgc:91895 Protein, CDPX2 Protein, CHO2 Protein, CPX Protein, CPXD Protein, AI255399 Protein, Pabp Protein, Td Protein, mSI Protein, emopamil binding protein (sterol isomerase) Protein, emopamil binding protein (sterol isomerase) L homeolog Protein, phenylalkylamine Ca2+ antagonist (emopamil) binding protein Protein, Ebp Protein, ebp.L Protein, ebp Protein, EBP Protein

Hintergrund: The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2 also known as Conradi-Hunermann syndrome).

Molekulargewicht: 26.2 kDa

NCBI Accession: NP_006570