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EBP Produkte

(Emopamil Binding Protein (Sterol Isomerase) (EBP))
The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2\; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008].

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Ausgewählte EBP Kategorien

EBP Antikörper

High quality antibodies with extensive validation data.

EBP ELISA Kits

Reliable ELISA kits for a wide range of species.

EBP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene EBP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC, WB
Validierungen
  • (4)
Kat. Nr. ABIN7142288
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation IHC, ELISA, WB
Validierungen
  • (2)
Kat. Nr. ABIN2158626
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN7266934
Menge 100 μL
Datenblatt Datenblatt

Empfohlene EBP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1118973
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1118974
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1118975
Menge 96 tests
Datenblatt Datenblatt

Empfohlene EBP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (4)
Kat. Nr. ABIN3079342
Menge 0.5 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3120933
Menge 0.25 mg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2712409
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren EBP Produkten

Ausavarat, Tanpaiboon, Tongkobpetch, Suphapeetiporn, Shotelersuk: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." in: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).

Lu, Dollé, Imholz, van t Slot, Verschuren, Wijmenga, Feskens, Boer: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).

Steijlen, van Geel, Vreeburg, Marcus-Soekarman, Spaapen, Castelijns, Willemsen, van Steensel: "Novel EBP gene mutations in Conradi-Hünermann-Happle syndrome." in: The British journal of dermatology, Vol. 157, Issue 6, pp. 1225-9, (2007) (PubMed).

Synonyme und alternative Namen zu EBP

emopamil binding protein (sterol isomerase) (Ebp), emopamil binding protein (sterol isomerase) L homeolog (ebp.L), emopamil binding protein (sterol isomerase) (ebp), emopamil binding protein (sterol isomerase) (EBP), phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), AI255399, cdpx2, CDPX2, cho2, CHO2, cpx, CPX, cpxd, CPXD, mSI, Pabp, Td, zgc:91895

Bezeichner auf Proteinebene für EBP

  • 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
  • D8-D7 sterol isomerase
  • emopamil-binding protein
  • cholestenol Delta-isomerase
  • phenylalkylamine binding protein
  • delta(8)-Delta(7) sterol isomerase
  • emopamil binding protein (sterol isomerase)
  • 3-beta-hydroxysteroid-delta-8,delta-7-isomerase
  • Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome)
  • emopamil-binding protein (sterol isomerase)
  • sterol 8-isomerase
  • phenylalkylamine Ca2+ antagonist (emopamil) binding protein
  • tattered
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