LRRC4 Protein (His tag)
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- Target Alle LRRC4 Proteine anzeigen
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses LRRC4 Protein ist gelabelt mit His tag.
- Applikation
- ELISA, Western Blotting (WB)
- Produktmerkmale
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Measured by its binding ability in a functional ELISA. Immobilized Recombinant mouse Netrin-G2a Fc chimera at 4 μg/mL, can bind rhLRRC4 with an apparent KD < 10 nM.
- Reinheit
- >92 % as determined by SDS-PAGE.
- Top Product
- Discover our top product LRRC4 Protein
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- Applikationshinweise
- This recombinant protein can be used for WB, ELISA. For research use only.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -80 °C,-20 °C
- Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Andere Bezeichnung
- NGL 2 (LRRC4 Produkte)
- Synonyme
- NGL-2 Protein, MBAG1 Protein, NLG-2 Protein, Nag14 Protein, leucine rich repeat containing 4 Protein, LRRC4 Protein, Lrrc4 Protein
- Hintergrund
- LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
- Molekulargewicht
- 55.6 kDa
- Gen-ID
- 64101
- UniProt
- Q9HBW1
- Pathways
- Synaptic Membrane
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