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Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-527) protein (His tag)

LRRC4 Spezies: Human Wirt: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Produktnummer ABIN2181482
$319.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle LRRC4 Proteine anzeigen
    LRRC4
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 39-527
    Spezies
    • 4
    • 3
    • 1
    Human
    Quelle
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses LRRC4 Protein ist gelabelt mit His tag.
    Sequenz
    AA 39-527
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.6 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >92 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    LRRC4
    Andere Bezeichnung
    LRRC4 (LRRC4 Produkte)
    Synonyme
    NGL-2, MBAG1, NLG-2, Nag14, leucine rich repeat containing 4, LRRC4, Lrrc4
    Hintergrund
    LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
    Molekulargewicht
    55.8 kDa
    Pathways
    Synaptic Membrane
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