IL18BP Protein (Fc Tag)

Produktnummer ABIN2566702

Produktdetails

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL18BP Protein ist gelabelt mit Fc Tag.

Applikation: Western Blotting (WB)

Produktmerkmale:

Fusion tag: C-Fc Tag

Reinheit: >95 % as determined by SDS-PAGE.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB. For research use only.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM tris, 100 mM glycine, pH 7.5

Lagerung: -80 °C,-20 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Andere Bezeichnung: IL18 BP (IL18BP Produkte)

Synonyme: IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein

Hintergrund: Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.

Molekulargewicht: 44.3 kDa

Gen-ID: 10068

NCBI Accession: NP_001138529

UniProt: O95998