KLF4 Protein (TAT tag)
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- Target Alle KLF4 Proteine anzeigen
- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses KLF4 Protein ist gelabelt mit TAT tag.
- Sequenz
- MAVSDALLPS FSTFASGPAG REKTLRQAGA PNNRWREELS HMKRLPPVLP GRPYDLAAAT VATDLESGGA GAACGGSNLA PLPRRETEEF NDLLDLDFIL SNSLTHPPES VAATVSSSAS ASSSSSPSSS GPASAPSTCS FTYPIRAGND PGVAPGGTGG GLLYGRESAP PPTAPFNLAD INDVSPSGGF VAELLRPELD PVYIPPQQPQ PPGGGLMGKF VLKASLSAPG SEYGSPSVIS VSKGSPDGSH PVVVAPYNGG PPRTCPKIKQ EAVSSCTHLG AGPPLSNGHR PAAHDFPLGR QLPSRTTPTL GLEEVLSSRD CHPALPLPPG FHPHPGPNYP SFLPDQMQPQ VPPLHYQELM PPGSCMPEEP KPKRGRRSWP RKRTATHTCD YAGCGKTYTK SSHLKAHLRT HTGEKPYHCD WDGCGWKFAR SDELTRHYRK HTGHRPFQCQ KCDRAFSRSD HLALHMKRHF GGYGRKKRRQ RRR
- Produktmerkmale
- Endotoxin level is less than 0.1 ng per ug (1EU/μg).
- Reinheit
- < 90 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per ug (1 EU/μg).
- Top Product
- Discover our top product KLF4 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Handhabung
- As with any protein, exposing KLF4-TAT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted KLF4-TAT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Haltbarkeit
- 24 months
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- Target
- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
- Andere Bezeichnung
- KLF4 (KLF4 Produkte)
- Synonyme
- EZF Protein, GKLF Protein, Gklf Protein, Zie Protein, KLF4 Protein, biklf Protein, biklf-A Protein, Kruppel like factor 4 Protein, Kruppel-like factor 4 (gut) Protein, Kruppel-like factor 4 Protein, Kruppel-like factor 4 (gut) L homeolog Protein, KLF4 Protein, Klf4 Protein, klf4 Protein, klf4.L Protein
- Hintergrund
- KLF4 is a member of the Kruppel-like factor (KLF) family of zinc finger transcription factors. Members of this family have in common 3 contiguous C2H2-type zinc fingers at the carboxyl terminus that comprise the DNA-binding domain. KLF4 is highly expressed in skin and gut epithelial tissues, but is also found in various other cells and tissues, including vascular endothelial cells, lymphocytes, lung, and testis. It is an important regulator of the cell cycle, transcription, and cell differentiation. Together with Sox2, Oct4, and cMyc, KLF4 can induce the reprogramming of primary human fibroblasts to a pluripotent state. KLF4 and other transcription factors can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant human KLF4-TAT is a 51.7 kDa protein containing 483 amino acid residues, including 13- residue C-terminal TAT peptide.
- Gen-ID
- 9314
- NCBI Accession
- NP_004226
- OMIM
- 194248077
- UniProt
- O43474
- Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
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