VSIG4 Protein (AA 20-283) (His tag)

Produktnummer ABIN2181925

Produktdetails

Target: VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-283

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VSIG4 Protein ist gelabelt mit His tag.

Sequenz: AA 20-283

Produktmerkmale: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE).

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))

Andere Bezeichnung: VSIG4 (VSIG4 Produkte)

Synonyme: DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein

Hintergrund: V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.

Molekulargewicht: 30.1 kDa