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Decorin (DCN) (AA 17-359) protein (His tag) Protein

DCN Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN2180962
$308.00
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  • Target Alle Decorin (DCN) Proteine anzeigen
    Decorin (DCN)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 17-359
    Spezies
    • 11
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Decorin Protein ist gelabelt mit His tag.
    Sequenz
    AA 17-359
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.8 kDa. The protein migrates as 45 kDa or higher under reducing (R) condition (SDS-PAGE) due to different glycosylation.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    Decorin (DCN)
    Andere Bezeichnung
    Decorin (DCN Produkte)
    Synonyme
    CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, DC, mDcn, cscd, dspg2, pg40, pgii, pgs2, slrr1b, decorin, decorin L homeolog, DCN, Dcn, dcn.L, dcn
    Hintergrund
    Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
    Molekulargewicht
    38.8 kDa
    NCBI Accession
    NP_001911
    Pathways
    Glycosaminoglycan Metabolic Process
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