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Decorin Protein (DCN) (His tag)

DCN Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Produktnummer ABIN7320511
  • Target Alle Decorin (DCN) Proteine anzeigen
    Decorin (DCN)
    Protein-Typ
    Recombinant
    Spezies
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Decorin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Mouse Decorin/DCN Protein (His Tag)
    Sequenz
    Gly17-Lys354
    Produktmerkmale
    Recombinant Mouse Decorin is produced by our Mammalian expression system and the target gene encoding Gly17-Lys354 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by SDS-PAGE
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DCN Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Decorin (DCN)
    Andere Bezeichnung
    Decorin/DCN (DCN Produkte)
    Synonyme
    CSCD Protein, DSPG2 Protein, PG40 Protein, PGII Protein, PGS2 Protein, SLRR1B Protein, DC Protein, mDcn Protein, cscd Protein, dspg2 Protein, pg40 Protein, pgii Protein, pgs2 Protein, slrr1b Protein, decorin Protein, decorin L homeolog Protein, DCN Protein, Dcn Protein, dcn.L Protein, dcn Protein
    Hintergrund

    Background: Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80 % and 78 % aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane and calcium homeostasis, keratinocyte function, and suppression of angiogenesis. Most recently, soluble decorin has been shown to induce autophagy in endothelial cells and mitophagy in breast carcinoma cells.

    Synonym: Decorin, Bone proteoglycan II, PG-S2, PG40, Dcn

    Molekulargewicht
    39.0 kDa
    UniProt
    P28654
    Pathways
    Glycosaminoglycan Metabolic Process
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