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Transferrin Receptor Protein (AA 89-760) (His tag)

TFRC Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2180829
  • Target Alle Transferrin Receptor (TFRC) Proteine anzeigen
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 89-760
    Spezies
    • 17
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Quelle
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Transferrin Receptor Protein ist gelabelt mit His tag.
    Sequenz
    AA 89-760
    Produktmerkmale
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Biological Activity Comment
    Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized rh CD71 /TFR at 10 μg/mL ( 100 μL/well ) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/mL.
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    Discover our top product TFRC Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Andere Bezeichnung
    CD71 (TFRC Produkte)
    Synonyme
    Trfr Protein, LOC100219280 Protein, tfr Protein, cd71 Protein, tfr1 Protein, trfr Protein, CD71 Protein, T9 Protein, TFR Protein, TFR1 Protein, TR Protein, TRFR Protein, p90 Protein, 2610028K12Rik Protein, AI195355 Protein, AI426448 Protein, AU015758 Protein, E430033M20Rik Protein, Mtvr-1 Protein, Mtvr1 Protein, transferrin receptor Protein, TFRC Protein, Tfrc Protein, tfrc Protein
    Hintergrund
    CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
    Molekulargewicht
    77.0 kDa
    NCBI Accession
    NP_003225
    UniProt
    P02786
    Pathways
    Transition Metal Ion Homeostasis
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