Transferrin Receptor Protein (His-Avi Tag)
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- Target Alle Transferrin Receptor (TFRC) Proteine anzeigen
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Transferrin Receptor Protein ist gelabelt mit His-Avi Tag.
- Sequenz
- Cys89-Phe760
- Reinheit
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human Transferrin R, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-Transferrin R Antiboy, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. The affinity constant of 27.50 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product TFRC Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Andere Bezeichnung
- Transferrin R (TFRC Produkte)
- Synonyme
- Trfr Protein, LOC100219280 Protein, tfr Protein, cd71 Protein, tfr1 Protein, trfr Protein, CD71 Protein, T9 Protein, TFR Protein, TFR1 Protein, TR Protein, TRFR Protein, p90 Protein, 2610028K12Rik Protein, AI195355 Protein, AI426448 Protein, AU015758 Protein, E430033M20Rik Protein, Mtvr-1 Protein, Mtvr1 Protein, transferrin receptor Protein, TFRC Protein, Tfrc Protein, tfrc Protein
- Hintergrund
- TR, TfR1, CD71, sTfR, T9, p90, TFRC, TFR,The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
- Molekulargewicht
- 77.9 kDa. Due to glycosylation, the protein migrates to 78-80 kDa based on Tris-Bis PAGE result.
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
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