FGF21 Protein (AA 29-209) (His tag)

Produktnummer ABIN2017777

Produktdetails

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 29-209

Spezies: Human

Quelle: CHO Cells

Aufreinigungstag / Konjugat: Dieses FGF21 Protein ist gelabelt mit His tag.

Produktmerkmale: ED50<0.3 μg/mL, measured in a bioassay using NIH-3T3 cells.
AA 29-209, expressed with C-terminal 6×His.

Reinheit: > 95 % as analyzed by SDS-PAGE.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human FGF-21 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human FGF-21, His should be stable up to 1 week at 4°C or up to 2 months at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Andere Bezeichnung: FGF-21 (FGF21 Produkte)

Synonyme: FGF21 Protein, fibroblast growth factor 21 Protein, FGF21 Protein, fgf21 Protein, Fgf21 Protein

Hintergrund: FGF-21, also known as fibroblast growth factor-21 and FGFL, is a secreted growth factor belonging to theheparin-binding growth factor family. It is produced by hepatocytes in response to fatty acid stimulation. FGF-21 couples with its co-factor beta-Klotho to signal through FGFR1c and FGFR4. Signal transduction results in insulin-independent uptake of glucose by adipocytes. Clinical administration of FGF-21 induces energy expenditure, fat utilization and lipid excretion.
Synonyms: fibroblast growth factor-21, FGFL

Molekulargewicht: 23-25 kDa, observed by reducing SDS-PAGE.

UniProt: Q9NSA1

Pathways: RTK Signalweg