Cytochrome C Protein (AA 2-105) (His tag)

Produktnummer ABIN1692193

Produktdetails

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-105

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Cytochrome C Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cytochrome C/CYCS (C-6His)

Sequenz: GDVEKGKKIF IMKCSQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGYSYTA ANKNKGIIWG EDTLMEYLEN PKKYIPGTKM IFVGIKKKEE RADLIAYLKK ATNELEHHHH HH

Produktmerkmale: Recombinant Human Cytochrome C/CYCS is produced with our E. coli expression system. The target protein is expressed with sequence (Gly2-Glu105) of Human CYCS fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.15M NaCl, 20 % Glycerol, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Andere Bezeichnung: CYCS (CYCS Produkte)

Synonyme: CYC Protein, HCS Protein, THC4 Protein, cyct Protein, cyc Protein, hcs Protein, CYCS Protein, cytc Protein, CYCSA Protein, CG17903 Protein, Cyt C Protein, Cyt c Protein, Cyt-c2 Protein, CytC-2 Protein, Cytc Protein, Cytc-p Protein, DC4 Protein, DMc01 Protein, Dmel\\CG17903 Protein, cyt c Protein, cyt c-p Protein, cyt-c-p Protein, cyt-c2 Protein, cyt.c Protein, cytochrome c Protein, dc4 Protein, pDMc01 Protein, wu:fk52b01 Protein, zgc:86706 Protein, ENSMUSG00000058927 Protein, cytochrome c, somatic Protein, cytochrome c, somatic S homeolog Protein, Cytochrome c proximal Protein, cytochrome c, somatic b Protein, cytochrome c, somatic pseudogene Protein, cytochrome c-like Protein, cytochrome c Protein, CYCS Protein, cycs.S Protein, cycs Protein, Cycs Protein, Cyt-c-p Protein, cycsb Protein, Gm10053 Protein, LOC100724240 Protein, CYC Protein, LOC100847700 Protein, LOC101107954 Protein, LOC106829744 Protein, LOC106992390 Protein, LOC102085712 Protein

Sub Type: Fusionprotein

Hintergrund: Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Alternative Names: Cytochrome C, CYCS, CYC

Molekulargewicht: 12.8 kDa

UniProt: P99999

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity