SH2D1A Protein (AA 1-128) (His tag)

Produktnummer ABIN1692037

Produktdetails

Target: SH2D1A (SH2 Domain Containing 1A (SH2D1A))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-128

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SH2D1A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SH2 Domain-Containing Protein 1A/SH2D1A/SAP/DSHP (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

Produktmerkmale: Recombinant Human SH2 Domain-Containing Protein 1A/SH2D1A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro128) of Human SH2D1A fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 10 % Glycerol, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: SH2D1A (SH2 Domain Containing 1A (SH2D1A))

Andere Bezeichnung: SH2D1A (SH2D1A Produkte)

Synonyme: DSHP Protein, EBVS Protein, IMD5 Protein, LYP Protein, MTCP1 Protein, SAP Protein, SAP/SH2D1A Protein, XLP Protein, XLPD Protein, RGD1562408 Protein, Gm686 Protein, SH2D1A Protein, SH2 domain containing 1A Protein, SH2D1A Protein, Sh2d1a Protein

Sub Type: Fusionprotein

Hintergrund: SH2 Domain-Containing Protein 1A,(SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Alternative Names: SH2 Domain-Containing Protein 1A, Duncan Disease SH2-Protein, Signaling Lymphocytic Activation Molecule-Associated Protein, SLAM-Associated Protein, T-Cell Signal Transduction Molecule SAP, SH2D1A, DSHP, SAP

Molekulargewicht: 16.3 kDa

UniProt: O60880

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process