BCMA Protein (AA 1-46, Extracellular Domain) (Fc Tag)

Produktnummer ABIN1344200

Produktdetails

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: Extracellular Domain, AA 1-46

Spezies: Human, Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BCMA Protein ist gelabelt mit Fc Tag.

Applikation: SDS-PAGE (SDS)

Spezifität: Binds mouse and human BAFF and APRIL.

Kreuzreaktivität: Human, Maus

Produktmerkmale: The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.01EU/μg purified protein (LAL test, Lonza).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with 50 μL sterile water.

Konzentration: Lot specific

Buffer: Lyophilized. Contains PBS.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Andere Bezeichnung: BCMA (TNFRSF17 Produkte)

Synonyme: TNFRSF17 Protein, BCM Protein, BCMA Protein, CD269 Protein, TNFRSF13A Protein, Tnfrsf13 Protein, Tnfrsf13a Protein, TNF receptor superfamily member 17 Protein, tumor necrosis factor receptor superfamily, member 17 Protein, Tnfrsf17 Protein, TNFRSF17 Protein

Hintergrund: BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.

Molekulargewicht: ~35kDa (SDS-PAGE)

UniProt: O88472