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BCMA Produkte

(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Kategorien

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].

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Ausgewählte BCMA Kategorien

BCMA Antikörper

High quality antibodies with extensive validation data.

BCMA ELISA Kits

Reliable ELISA kits for a wide range of species.

BCMA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BCMA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, FACS, IP, IF
Validierungen
  • (8)
Kat. Nr. ABIN6961043
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7076067
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7172255
Menge 100 μL
Datenblatt Datenblatt

Empfohlene BCMA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970980
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975649
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960291
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BCMA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7273940
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7273941
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7273936
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BCMA Produkten

Berahovich, Liu, Zhou, Tsadik, Xu, Golubovskaya, Wu: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).

Chapellier, Peña-Martínez, Ramakrishnan, Eriksson, Safaee-Talkhoncheh, Orsmark-Pietras, Lilljebjörn, Högberg, Hagström-Andersson, Fioretos, Larsson, Järås: "Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells." in: Haematologica, (2019) (PubMed).

Garfall, Stadtmauer, Hwang, Lacey, Melenhorst, Krevvata, Carroll, Matsui, Wang, Dhodapkar, Dhodapkar, Das, Vogl, Weiss, Cohen, Mangan, Ayers, Nunez-Cruz, Kulikovskaya, Davis, Lamontagne, Dengel, Kerr et al.: "Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. ..." in: JCI insight, Vol. 3, Issue 8, (2018) (PubMed).

Bu, Singh, Choi, Ruella, Nunez-Cruz, Mansfield, Bennett, Barton, Wu, Zhang, Wang, Wei, Cogan, Ezell, Joshi, Latimer, Granda, Tschantz, Young, Huet, Richardson, Milone: "Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma." in: Oncotarget, Vol. 9, Issue 40, pp. 25764-25780, (2018) (PubMed).

Berahovich, Zhou, Xu, Wei, Guan, Guan, Harto, Fu, Yang, Zhu, Li, Wu, Golubovskaya: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).

de la Varga Martínez, Rodríguez-Bayona, Añez, Medina Varo, Pérez Venegas, Brieva, Rodríguez: "Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation." in: European journal of immunology, Vol. 47, Issue 7, pp. 1211-1219, (2017) (PubMed).

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).

Laurent, Hoffmann, Kuhn, Cheng, Chu, Schmidt-Supprian, Hauck, Schuh, Krumbholz, Rübsamen, Wanngren, Khademi, Olsson, Alexander, Hiepe, Pfister, Weber, Jenne, Wekerle, Hohlfeld, Lichtenthaler, Meinl: "γ-Secretase directly sheds the survival receptor BCMA from plasma cells." in: Nature communications, Vol. 6, pp. 7333, (2015) (PubMed).

Hoffmann, Kuhn, Laurent, Hauck, Berer, Wendlinger, Krumbholz, Khademi, Olsson, Dreyling, Pfister, Alexander, Hiepe, Kümpfel, Crawford, Wekerle, Hohlfeld, Lichtenthaler, Meinl: "The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 542-52, (2015) (PubMed).

Khan, Hams, Floudas, Sparwasser, Weaver, Fallon: "PD-L1hi B cells are critical regulators of humoral immunity." in: Nature communications, Vol. 6, pp. 5997, (2015) (PubMed).

Synonyme und alternative Namen zu BCMA

TNF receptor superfamily member 17 (Tnfrsf17), TNF receptor superfamily member 17 (TNFRSF17), tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17), BCM, BCMA, CD269, Tnfrsf13, TNFRSF13A, Tnfrsf13a, TNFRSF17

Bezeichner auf Proteinebene für BCMA

  • tumor necrosis factor receptor superfamily member 17
  • tumor necrosis factor receptor superfamily, member 17
  • B cell maturation antigen
  • B-cell maturation factor
  • B-cell maturation protein
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