CD3G Protein (His tag)

Produktnummer ABIN1098786

Produktdetails

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CD3G Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, T3G

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Andere Bezeichnung: CD3G (CD3G Produkte)

Synonyme: Ctg-3 Protein, Ctg3 Protein, T3g Protein, CD3-GAMMA Protein, T3G Protein, CD3 antigen, gamma polypeptide Protein, CD3g molecule Protein, Cd3g Protein, CD3G Protein

Hintergrund: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 13.1 kDa (117aa)

NCBI Accession: NP_000064

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events