KCTD11 Protein (His tag)

Produktnummer ABIN7280167

Produktdetails

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses KCTD11 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: BTB/POZ domain-containing protein KCTD11, C17orf36, KCASH1, MGC129844, REN, REN/KCTD11

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Andere Bezeichnung: KCTD11 (KCTD11 Produkte)

Synonyme: KCTD11 Protein, AF465352 Protein, Ren Protein, C17orf36 Protein, KCASH1 Protein, REN Protein, REN/KCTD11 Protein, potassium channel tetramerization domain containing 11 Protein, potassium channel tetramerisation domain containing 11 Protein, KCTD11 Protein, Kctd11 Protein

Hintergrund: BTB/POZ domain-containing protein KCTD11, is a 232 amino acid regulator of neuronal differentiation that induces growth arrest, apoptosis and the expression of p27, a cyclin-dependent kinase inhibitor. Expressed at highest levels in cerebellum, KCTD11 functions as an antagonist of the Hedgehog pathway and activator of the caspase cascade. Recombinant human KCTD11 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 28 kDa (252aa)

NCBI Accession: NP_001002914

Pathways: Hedgehog Signalweg