HBXIP Protein (His tag)

Produktnummer ABIN1098350

Produktdetails

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HBXIP Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Hepatitis B virus x interacting protein, XIP

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM EDTA

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Andere Bezeichnung: HBXIP (HBXIP Produkte)

Synonyme: HBXIP Protein, xip Protein, XIP Protein, 1110003H18Rik Protein, Hbxip Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Protein, Hepatitis B virus X-interacting protein Protein, LAMTOR5 Protein, xip Protein, Lamtor5 Protein

Substanzklasse: Viral Protein

Hintergrund: Hepatitis B virus x interacting protein, also known as HBXIP, was originally identified by its ability to form a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates the activity of HBX and alters the replicative life cycle of the virus. In addition, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly through an interaction with Dynein light chain. Recombinant human HBXIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 20.7 kDa (197aa) confirmed by MALDI-TOF

NCBI Accession: NP_006393

Pathways: PI3K-Akt Signalweg, Regulation of Cell Size