RHOG Protein (His tag)

Produktnummer ABIN1098313

Produktdetails

Target: RHOG (Ras Homolog Family Member G (RHOG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RHOG Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Rho-related GTP-binding protein RhoG, ARHG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 40% glycerol, 5 MM DTT, 200 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: RHOG (Ras Homolog Family Member G (RHOG))

Andere Bezeichnung: RhoG (RHOG Produkte)

Synonyme: 2810426G09Rik Protein, Arhg Protein, Sid10750 Protein, ARHG Protein, rhog Protein, zgc:55848 Protein, wu:fk30f01 Protein, arhg Protein, rhoga Protein, zgc:66008 Protein, ras homolog family member G Protein, ras homolog family member Gb Protein, ras homolog family member G S homeolog Protein, ras homolog gene family, member Gd Protein, Rhog Protein, rhogb Protein, RHOG Protein, rhog.S Protein, rhogd Protein

Hintergrund: RhoG(Ras homology Growth-related) is a member of the Rac subfamily of the Rho family of small G proteins. RhoG is a small monomeric GTP-binding protein (G protein), and is an important component of many intracellular signalling pathways. This protien are required for the formation of membrane ruffles during macropinocytosis. It plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. Like most small G proteins RhoG is involved in a diverse set of cellular signalling mechanisms. In mammalian cells these include cell motility, gene transcription, endocytosis, neurite outgrowth, protection from anoikis and regulation of the neutrophil NADPH oxidase. Recombinant human RhoG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 25.2kDa (225aa) confirmed by MALDI-TOF

NCBI Accession: NP_001656

Pathways: RTK Signalweg