NEIL2 Protein (His tag)
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- Target Alle NEIL2 Proteine anzeigen
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses NEIL2 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Aufreinigung
- purified by chromatography
- Reinheit
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NEIL2 Protein
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Endonuclease 8-like 2 (NEIL2) (AA 1-332) protein (His tag)
NEIL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Endonuclease 8-like 2 (NEIL2) (AA 1-332) protein (GST tag)NEIL2 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Endonuclease 8-like 2 (NEIL2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NEIL2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Endonuclease 8-like 2 (NEIL2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NEIL2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Kommentare
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Synonyms: Endonuclease 8-like 2, NEH2, NEI2, Nei-like protein 2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT, 10% glycerol, 0.1 M NaCl
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Andere Bezeichnung
- NEIL2 (NEIL2 Produkte)
- Synonyme
- NEH2 Protein, NEI2 Protein, Gm1212 Protein, nei like DNA glycosylase 2 Protein, nei like 2 (E. coli) Protein, NEIL2 Protein, Neil2 Protein
- Hintergrund
- Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, and xanthine. Recombinant human NEIL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 39.4 kDa (356aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_659480
- Pathways
- DNA Reparatur
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