SERPINA3 Protein (AA 24-423) (His tag)

Produktnummer ABIN1097505

Produktdetails

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-423

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SERPINA3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Serpin A3/alpha-1-Antichymotrypsin (C-6His)

Sequenz: HPNSPLDEEN LTQENQDRGT HVDLGLASAN VDFAFSLYKQ LVLKAPDKNV IFSPLSISTA LAFLSLGAHN TTLTEILKGL KFNLTETSEA EIHQSFQHLL RTLNQSSDEL QLSMGNAMFV KEQLSLLDRF TEDAKRLYGS EAFATDFQDS AAAKKLINDY VKNGTRGKIT DLIKDLDSQT MMVLVNYIFF KAKWEMPFDP QDTHQSRFYL SKKKWVMVPM MSLHHLTIPY FRDEELSCTV VELRYTGNAS ALFILPDQDK MEEVEAMLLP ETLKRWRDSL EFREIGELYL PKFSISRDYN LNDILLQLGI EEAFTSKADL SGITGARNLA VSQVVHKAVL DVFEEGTEAS AATAVKITLL SALVETRTIV RFNRPFLMII VPTDTQNIFF MSKVTNPKQA VDHHHHHH

Produktmerkmale: Recombinant Human Serpin A3 produced by transfected human cells is a secreted protein with sequence (His24-Ala423) of Human SERPIN A3 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Andere Bezeichnung: alpha-1-antichymotrypsin (SERPINA3 Produkte)

Synonyme: SERPINA3-1 Protein, Pi2 Protein, AACT Protein, ACT Protein, GIG25 Protein, A1AT Protein, PI Protein, alpha-1-PI Protein, AAT Protein, Pi Protein, Spi1 Protein, SERPINA3-5 Protein, serpina3 Protein, serpin A3-5 Protein, serpin family A member 3 Protein, alpha-1-antiproteinase F precursor Protein, serpin family A member 1 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog Protein, LOC396684 Protein, SERPINA3 Protein, LOC100008973 Protein, SERPINA1 Protein, Serpina1 Protein, SPIA5 Protein, serpina3.L Protein

Sub Type: Fusionprotein

Hintergrund: Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.
Alternative Names: Alpha-1-Antichymotrypsin, ACT, Cell Growth-Inhibiting Gene 24/25 Protein, Serpin A3, SERPINA3, AACT

Molekulargewicht: 46.33 kDa

UniProt: P01011