MBL2 Protein (AA 21-248) (His tag)

Produktnummer ABIN1097140

Produktdetails

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-248

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses MBL2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Mannose-Binding Protein C/MBL-2/MBP- C(C-6His)

Sequenz: ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH LAVCEFPIVD HHHHHH

Produktmerkmale: Recombinant Human Mannose-Binding Protein C/MBL-2 produced by transfected human cells is a secreted protein with sequence (Glu21-Ile248) of human MBL-2 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Andere Bezeichnung: mbl-2 (MBL2 Produkte)

Synonyme: COLEC1 Protein, HSMBPC Protein, MBL Protein, MBL2D Protein, MBP Protein, MBP-C Protein, MBP1 Protein, MBPD Protein, pMBP-27 Protein, mbl2 Protein, MBL1 Protein, cMBl Protein, collectin Protein, Ab2-001 Protein, Ab2-011 Protein, L-MBP Protein, MBL-C Protein, COLEC2 Protein, mbl Protein, etID42583.2 Protein, fb68b07 Protein, hbl3 Protein, wu:fb68b07 Protein, zgc:109836 Protein, mannose binding lectin 2 Protein, Mannose-binding protein C Protein, mannose-binding lectin (protein C) 2, soluble Protein, mannose-binding lectin (protein C) 2 Protein, mannose-binding lectin family member 3, pseudogene Protein, MBL2 Protein, mbl2 Protein, Mbl2 Protein, MBL3P Protein

Sub Type: Fusionprotein

Hintergrund: Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an alpha-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These homotrimers further associates into oligomeric structures of up to 6 units. Whereas two forms of MBL proteins exist in rodents and other animals. Human MBL-2 is 25 kDa. Human MBL-2 is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteine-rich region, a 58 aa collagen-like segment and a 111 aa C-type lectin domain that binds to neutral bacterial carbohydrates.
Alternative Names: Mannose-Binding Protein C, MBP-C, Collectin-1, MBP1, Mannan-Binding Protein, Mannose-Binding Lectin, MBL2, COLEC1, MBL

Molekulargewicht: 25.06 kDa

UniProt: P11226

Pathways: Komplementsystem, Positive Regulation of Immune Effector Process