IL1RAP Protein (AA 21-356) (His tag)

Produktnummer ABIN1096885

Produktdetails

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-356

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses IL1RAP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-6His)

Sequenz: SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKFNYST AHSAGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT YCSKVAFPLE VVQKDSCFNS PMKLPVHKLY IEYGIQRITC PNVDGYFPSS VKPTITWYMG CYKIQNFNNV IPEGMNLSFL IALISNNGNY TCVVTYPENG RTFHLTRTLT VKVVGSPKNA VPPVIHSPND HVVYEKEPGE ELLIPCTVYF SFLMDSRNEV WWTIDGKKPD DITIDVTINE SISHSRTEDE TRTQILSIKK VTSEDLKRSY VCHARSAKGE VAKAAKVKQK GNRCGQVDHH HHHH

Produktmerkmale: Recombinant Human Interleukin-1 Receptor Accessory Protein/IL-1RAcP produced by transfected human cells is a secreted protein with sequence (Ser21-Gln356) of Human IL1RAP fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Andere Bezeichnung: Il-1-r3 (IL1RAP Produkte)

Synonyme: IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein

Sub Type: Fusionprotein

Hintergrund: Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1alpha, IL1betaand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
Alternative Names: Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, Interleukin-1 Receptor 3, IL-1R-3, IL-1R3, IL1RAP, C3orf13, IL1R3

Molekulargewicht: 39.75 kDa

UniProt: Q9NPH3

Pathways: NF-kappaB Signalweg, Growth Factor Binding