Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-UBE2L3 antibody (Catalog #: ARP43026_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
UBE2L3(ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E2-F1, L-UBC, UBCH7, UbcM4
Protein Interaction Partner: UBE3A,ARIH1,ARIH2,BRCA1,CBL,CCNB1IP1,CUL9,NEDD4,NEDD4L,PARK2,PTEN,RNF144A,RNF144B,RNF19A,RNF216,SMAD4,UBE3A,UBOX5,ARIH1,ARIH1,ARIH2,ARIH2,AURKA,BRCA1,CBL,CBL,CUL9,EIF4E2,ITCH,NEDD4,POLR2A,PTEN,RNF19A,RNF216,RSP5,SMURF2,UBASH3A,UBE3A,UBOX5,Ubox5,WWP2